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One or more keywords matched the following items that are connected to Awad, Issam
Item TypeName
Concept rho-Associated Kinases
Academic Article Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity.
Academic Article A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease.
Academic Article Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease.
Academic Article Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations.
Academic Article Lesions from patients with sporadic cerebral cavernous malformations harbor somatic mutations in the CCM genes: evidence for a common biochemical pathway for CCM pathogenesis.
Academic Article Peripheral plasma vitamin D and non-HDL cholesterol reflect the severity of cerebral cavernous malformation disease.
Academic Article Micro-computed tomography in murine models of cerebral cavernous malformations as a paradigm for brain disease.
Academic Article RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations.
Academic Article The cerebral cavernous malformation disease causing gene KRIT1 participates in intestinal epithelial barrier maintenance and regulation.
Academic Article Phenotypic characterization of murine models of cerebral cavernous malformations.
Academic Article Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.
Academic Article A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease.
Grant Development of BA-1049 for treatment of cerebral cavernous malformation
Academic Article Role of Rho-Associated Kinase in the Pathophysiology of Cerebral Cavernous Malformations.
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  • rho Associated Kinases